Patent · US Expired

Use, in a composition, as cyclooxygenase activator and/or stabilizer, of at least one pyrimidine derivative sustituted at the 6th position and a cyclooxygenase substrate

US5756092A · kind A · utility

8Cited by
2References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 5, 1996
Grant dateMay 26, 1998
Priority date
Expiry dateApr 5, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2800/75
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A composition and a method of treating alopecia or dermatological conditions with said composition are disclosed. The composition comprises at least one pyrimidine derivative substituted at the 6th position that activates and/or stabilizes cyclooxygenase, a pharmaceutically or cosmetically acceptable carrier and/or adjuvant and one of the following: a cyclooxygenase enzyme or a cyclooxygenase enzyme and at least one cyclooxygenase substrate comprising a polyunsaturated fatty acid having at least 20 carbon atoms. The composition is applied topically to the affected area or can be administered systemically.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.