Use, in a composition, as cyclooxygenase activator and/or stabilizer, of at least one pyrimidine derivative sustituted at the 6th position and a cyclooxygenase substrate
US5756092A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 5, 1996 |
| Grant date | May 26, 1998 |
| Priority date | — |
| Expiry date | Apr 5, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/75
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition and a method of treating alopecia or dermatological conditions with said composition are disclosed. The composition comprises at least one pyrimidine derivative substituted at the 6th position that activates and/or stabilizes cyclooxygenase, a pharmaceutically or cosmetically acceptable carrier and/or adjuvant and one of the following: a cyclooxygenase enzyme or a cyclooxygenase enzyme and at least one cyclooxygenase substrate comprising a polyunsaturated fatty acid having at least 20 carbon atoms. The composition is applied topically to the affected area or can be administered systemically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.