Antagonists of gonadotropin releasing hormone

US5756507A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Mark Goulet · Westfield, US
• Lin Chu · Scotch Plains, US
• Wallace T. Ashton · Edison, US
• Michael H. Fisher · Bound Brook, US
• Matthew J. Wyvratt · Mountainside, US
• Roy G. Smith · Houston, US
• Robert L. Bugianesi · Colonia, US
• Mitree M. Ponpipom · Readington, US
• Yi Yang · San Diego, US
• Peter Lin · Luzhu District, TW

Key dates

• Filing date: Dec 5, 1996
• Grant date: May 26, 1998
• Expiry date: Dec 5, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.