Biphenysulfonamide matrix metal alloproteinase inhibitors
US5756545A · kind A · utility
19Cited by
7References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 21, 1997 |
| Grant date | May 26, 1998 |
| Priority date | — |
| Expiry date | Apr 21, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/195
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R.sup.1 includes alkyl, halo, nitro, amino, cyano, alkoxy, and alkoxycarbonyl; R.sup.2 is alkyl and substituted alkyl; and R.sup.3 is OH or NHOH are useful for inhibiting matrix metalloproteinase enzymes in animals, and as such, prevent and treat diseases resulting from the breakdown of connective tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.