Protein imaging
US5756717A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | May 24, 1995 |
| Grant date | May 26, 1998 |
| Priority date | — |
| Expiry date | May 24, 2015 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/3852
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed are specifically designed binding, "protein imaged" sorbents which reversibly bind with high specificity and affinity a preselected macromolecule, specifically a protein. The sorbents define one or more cavities which have a binding surface complementary in shape to the molecular surface of the macromolecule and a plurality of positively and negatively charged chemical moieties spatially distributed in a mirror image and charge inverse of a subset of the ionizable groups on the molecular surface of the macromolecule. Also disclosed are methods of producing such sorbents, useful over a range of conditions, for both preparative and analytical chromatographic separations or for use in various types of analyses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.