Asymmetric hydrogenation of dihyrofuroimidazole derivatives
US5756756A · kind A · utility
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Key dates
| Filing date | Jul 22, 1997 |
| Grant date | May 26, 1998 |
| Priority date | — |
| Expiry date | Jul 22, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the asymmetric hydrogenation of the furoimidazole derivatives of the general formula: ##STR1## wherein R.sub.1 is a protective group, which is cleavable in a known way, and R.sub.2 is hydrogen or a protective group, which is cleavable in a known way, with hydrogen in the presence of a homogeneous catalyst to the corresponding diastereomeric tetrahydrofuroimidazole derivatives of the general formula: ##STR2## The tetrahydrofuroimidazole derivatives of the general formula II are intermediate products for the production of vitamin (+) biotin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.