4, 4'-bridged bis-2, 4-diaminoquinazolines

US5760230A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rudolf Schohe-Loop · Wuppertal, DE
• Peter-Rudolf Seidel · Cologne, DE
• William Bullock · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Hans-Georg Lerchen · Leverkusen, DE
• Georg Terstappen · Düsseldorf, DE
• Joachim Schuhmacher · Wuppertal, DE
• Franz-Josef van der Staay · Dronten, NL
• Bernard Schmidt · Lindlar, DE
• Richard J. Fanelli · Madison, US
• Jane C. Chisholm · Clinton, US
• Richard T. McCarthy · Madison, US

Key dates

• Filing date: Oct 11, 1996
• Grant date: Jun 2, 1998
• Expiry date: Oct 11, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/95
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

4,4'-Bridged bis-2,4-diaminoquinazolines of the general formula (I) ##STR1## processes for their preparation and use as agents acting on the potassium channels of the brain.