Production and use of salts of 6, 8-bis (amidiniumthio) -octanoic acid

US5760268A · kind A · utility

Assignee

• Asta Medica Aktiengesellschaft · DE

Inventors

• Thomas Beisswenger · Radebeul, DE
• Rainer Gewald · Dresden, DE
• Alfred Olbrich · Halle (Westf.), DE
• Horst Bethge · Hanau, DE
• Frank Hubner · Ober-Ramstadt, DE
• Klaus Huthmacher · Gelnhausen, DE
• Herbert Klenk · Hanau, DE
• Roland Moller · Herbrechtingen, DE
• Stephan Rautenberg · Hanau, DE
• Gerhard Sator · Dieburg, DE

Key dates

• Filing date: Jan 21, 1997
• Grant date: Jun 2, 1998
• Expiry date: Jan 21, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C335/32
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to the production and purification of salts of 6,8-bis(amidiniumthio) octanoic acid, its enantiomers (+)-6,8-bis(amidiniumthio)octanoic acid and (-)-6,8-bis (amidiniumthio)octanoic acid and of the esters of these compounds as well as to their use to produce dihydrolipoic acid and .alpha.-lipoic acid.