Blood contact surfaces employing natural subendothelial matrix and methods for making and using the same
US5762600A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Jun 18, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2/06
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
This invention relates to improved vascular prostheses derived from mammalian blood vessels. The prostheses are fabricated from arterial segments from which the donor endothelium has been removed. A key aspect of this invention is the preservation of the subendothelial extracellular matrix that will serve as the blood interface of the vascular prostheses. The vessel segments are treated to reduce the likelihood of calcification and fixed with a tissue preservative. This invention results in vascular prostheses that are particularly useful for small diameter applications, such as arterial replacement requiring a diameter of 6 mm or less.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.