Isosorbide dinitrate-containing patch using a mixed adhesive
US5762954A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 28, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Aug 28, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an ISDN-containing patch that causes minimal occurrence of skin rash and has excellent percutaneous absorption and adhesive strength. The present invention discloses an isorbide dinitrate-containing patch comprising: an adhesive layer formed on a flexible support, wherein said layer comprises an adhesive composition containing adhesive and isosorbide dinitrate, the adhesive being composed of silicone-based adhesive (A) and polyvinyl acetate-based adhesive (B), their weight ratio being A:B=85:15 to 15:85, and the weight ratio of isosorbide dinitrate (C) to the adhesives (A+B) being (A+B):C=90:10 to 60:40.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.