Method of phosphate ester hydrolysis
US5763172A · kind A · utility
8Cited by
29References
28Claims
0Family size
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2531/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of phosphate ester hydrolysis including incubating a solution of an aqueous phosphate ester with a metallotexaphyrin complex under conditions and for a time sufficient to hydrolyze the phosphate ester. The metal is a metal cation having catalytic activity for ester bond hydrolysis in aqueous solution. Phosphate ester substrates include nucleic acid such as RNA, phosphoric anhydrides, phospholipids, and alkyl phosphate esters.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.