Universal binding film

US5763191A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Wolfgang Knoll · Mainz, DE
• Franz-Josef Schmitt · Leiwen, DE
• Christian Klein · Iffeldorf, DE
• Hans-Joachim Guder · Weilheim, DE
• Martha Liley · Saint-Blaise, CH
• Jurgen Spinke · Lorsch, DE

Key dates

• Filing date: Jul 25, 1994
• Grant date: Jun 9, 1998
• Expiry date: Jul 25, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/12556
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention concerns a binding matrix containing a carrier material and a solid phase reactant which is adsorbed to this via anchor groups that is capable of binding to at least one free reaction partner wherein the solid phase reactant forms a dilute and essentially laterally homogeneous binding layer on the surface of the carrier material. In addition a method for the determination of an analyte in a sample solution is claimed in which a solid phase reactant is used which is a component of a binding matrix according to the present invention. In this process the specific binding reaction is preferably determined by optical reflection techniques.