Nucleic acid encoding novel human G-protein coupled receptor
US5763218A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Aug 14, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Aug 14, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.