Transformant producing substance PF1022, and method for transforming microorganism belonging to the class hyphomycetes
US5763221A · kind A · utility
4Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 7, 1997 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Feb 7, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/645
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for transforming strain PF1022, which produces a cyclic depsipeptide (substance PF1022) and belongs to the order Agonomycetales of the class Hyphomycetes has been established by using a plasmid constructed with a promoter, a terminator, a marker gene and a target gene. When the strain PF1022 was transformed by this method, a gene encoding an enzyme, which is the target gene, was transduced into the host. As a result, the utilization of nutrients by the strain PF1022 was improved and, further, its cyclic depsipeptide productivity was also improved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.