Method and apparatus for producing position addressable combinatorial libraries
US5763263A · kind A · utility
178Cited by
12References
12Claims
0Family size
Inventor
Key dates
| Filing date | Jul 24, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Jul 24, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00237
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method and apparatus for producing combinatorial position-addressable libraries of different-sequence oligomers or different-substituent small molecule compounds are disclosed. The method employs massive parallel synthesis by stepwise subunit addition or substituent addition in a dense capillary-tube array. The libraries allow high throughput screening of library compounds in either solid phase or solution phase, and position-related identification of active library compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.