Ecdysis-triggering hormone compositions
US5763400A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 3, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Jan 3, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Unique ecdysis triggering hormone nucleic acid molecules and ETH peptides/proteins having biological activity for promoting ecdysis in insects are disclosed. Methods of preparing the peptides/proteins by recombinant means, and use of the peptide/proteins in an insect controlling agent are also provided. Methods of inducing ecdysis using the sequences encoding the ETH peptides/proteins are outlined. Insecticidal preparations that are specific to insects that shed their skin, and that do not pose an environmental threat to humans or animals, are also disclosed employing the nucleic and molecules and peptides and proteins they encode. Processes employing the ETH nucleic acid encoding sequences to identify ETH receptors are also defined. The ETH receptors are employed in screening assays to select organic molecules capable of binding the ETH receptor and inducing ecdysis and eclosion, particularly in insects. Methods of using the ETH nucleic acid molecules in genetic engineering of plants and insects are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.