Inhibitors of cell-medicated disorders
US5763480A · kind A · utility
5Cited by
3References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 14, 1994 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Feb 14, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L24/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or Tl-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or Tl-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and Tl, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.