Naphthalene derivatives as prostaglandin I.sub.2 agonsists
US5763489A · kind A · utility
9Cited by
0References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 10, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Oct 10, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the formula ##STR1## wherein R.sup.1 is carboxy or protected carboxy, PA1 R.sup.2 is hydrogen, hydroxy or protected hydroxy, PA1 R.sup.3 is hydrogen, hydroxy, protected hydroxy, etc., PA1 R.sup.4 is hydrogen or halogen, PA1 A.sup.1 is lower alkylene, PA1 A.sup.2 is bond or lower alkylene, PA1 --R.sup.5 is ##STR2## (in which R.sup.6 is mono(or di or tri)aryl(lower)alkyl and Z is N or CH), etc., and ##STR3## and a pharmaceutically acceptable salt thereof which are useful as medicaments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.