Methods for effecting memory enhancement mediated by non-steroidal sulfatase inhibitors
US5763492A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 1, 1996 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Oct 1, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention discloses a method for enhancing memory in a patient comprising administering a compound of formula ##STR1## wherein R.sub.1 and R.sub.2 are independently selected from the group consisting of hydrogen and a lower alkyl group; m is an integer between about 0 and 4; and n is an integer between about 5 and 14. The methods generally comprise administering an effective amount of the compound. The invention also discloses the enhancement of memory by the use of non-steroidal sulfatase inhibitors of the above formula in conjunction with the naturally occurring neurosteroids dehydroepiandrosterone sulfate (DHEAS) and/or pregnenolone sulfate (PS). The patients benefitting from the methods of the present invention will generally have an illness that causes memory loss, or will be individuals who otherwise want to improve memory.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.