Collagen derivatives, process for producing them and their application to the preparation of biomaterials
US5763579A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 16, 1995 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | Jun 16, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2310/00365
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention relates to a modified collagen which is soluble in water and/or in aprotic polar organic solvents and which comprises free or substituted thiol functional groups carried by residues of cysteine or its derivatives, the residues being, at least partially, residues which are directly grafted onto the collagen chain, characterized in that it possesses a level of free or substituted thiol functional groups greater than 0.3, preferably 0.5 mM/g of collagen. The invention also relates to the production of these new collagen derivatives and to their application in the preparation of biomaterials, it being possible for the latter to be used especially in the manufacture of implants, prostheses or the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.