Use of protease inhibitors and protease vaccines to protect animals from flea infestation
US5766609A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 18, 1994 |
| Grant date | Jun 16, 1998 |
| Priority date | — |
| Expiry date | Oct 18, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/858
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method to protect a host animal from flea infestation by treating that animal with a composition that includes a compound that reduces protease activity of fleas feeding from the treated animal, thereby reducing flea burden on the animal and in the environment of the animal. The present invention also relates to compositions including flea protease vaccines, anti-flea protease antibodies and/or protease inhibitors. Also included in the present invention are soluble flea midgut preparations, flea protease proteins, nucleic acid molecules encoding such proteins and antibodies that selectively bind to such proteins. The present invention also includes methods to obtain and use such preparations, proteins, nucleic acid molecules, antibodies and protease inhibitors to protect an animal from flea infestation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.