Circular RNA and uses thereof
US5766903A · kind A · utility
82Cited by
1References
49Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1995 |
| Grant date | Jun 16, 1998 |
| Priority date | — |
| Expiry date | Aug 23, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/67
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a product and process for producing polypeptides, such products including a circular RNA having a ribosome binding site that engages an eukaryotic ribosome and cells transformed with such circular RNA. Circular RNA is produced by linking the 5' and 3' ends of a desired linear RNA sequence, and such constructs can be used to produce desired amounts of polypeptides when such constructs are translated either in vitro or in vivo. The present invention also relates to the use of circular RNA as a pharmaceutical agent to treat cells and animals involved in a disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.