Method for identifying and producing a protease capable of cleaving the TNF receptor

US5766917A · kind A · utility

Assignee

• YEDA RESEARCH AND DEVELOPMENT CO. LTD. · IL

Inventors

• David Wallach · Rehovot, IL
• Cord Brakebusch · Braunschweig, DE
• Eugene Varfolomeev · Rehovot, IL
• Michael Batkin · Rehovot, IL

Key dates

• Filing date: Apr 28, 1997
• Grant date: Jun 16, 1998
• Expiry date: Apr 28, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Molecules which influence the shedding of the cell-bound p55 Tumor Necrosis Factor receptor (p55-TNF-R), are provided, together with methods of producing them.