Combination hydroxypropylamine library
US5766963A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 26, 1996 |
| Grant date | Jun 16, 1998 |
| Priority date | — |
| Expiry date | Jan 26, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/11
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A combinatorial library is disclosed which is represented by Formula ##STR1## wherein: ##STR2## is a solid support; T'-L- is an identifier residue; and -L'-II' is a ligand/linker residue. This library contains hydroxypropylamines of the formula: EQU Aa.sup.1 -Aa.sup.2 -(CH.sub.2 Ar.sup.1)-CH.sub.2 CHOH-CH.sub.2 XR.sup.1II wherein: PA1 Aa.sup.1 and Aa.sup.2 is each an amino acid joined to each other through an amide bond; PA1 Ar.sup.1 is an aromatic ring system; PA1 --CH.sub.2 Ar.sup.1 is attached to N on Aa.sup.2 ; and PA1 R.sup.1 is H, C.sub.1-20 alkyl, alkenyl, alkynyl, aryl, heteroaryl, aryl or heteroaryl fused to a 3- or 4-membered moiety to form a non-aromatic second ring, or substituted C.sub.1-20 alkyl, alkenyl, or alkynyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.