Patent · US Expired

Retinoid suppression of ventricular muscle cell hypertrophy

US5767155A · kind A · utility

3Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 22, 1996
Grant dateJun 16, 1998
Priority date
Expiry dateJul 22, 2016

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01D29/661
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

A method of suppressing ventricular muscle cell hypertrophy induced by an .alpha..sub.1 -adrenergic agonist or endothelin, by providing an effective amount of a retinoic acid compound. Also provided are methods for identifying compounds which suppress ventricular muscle cell hypertrophy, compounds which inhibit the retinoic acid suppression of ventricular muscle cell hypertrophy, and therapeutic methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.