Process for preparing cardiodilatin fragments; highly purified cardiodilatin fragments and intermediate products for the preparation of same

US5767239A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Hansueli Immer · Balsthal, CH
• Wolf-Georg Forssmann · Hannover, DE
• Knut Adermann · Hannover, DE
• Christian Klessen · Lauterecken, DE

Key dates

• Filing date: Dec 2, 1996
• Grant date: Jun 16, 1998
• Expiry date: Dec 2, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a process for the preparation of cardiodilatin fragments, to highly purified cardiodilatin fragments, and to appropriate intermediates for the preparation of said fragments. Furthermore, the invention relates to highly purified cardiodilatin fragments which are free of peptide impurities and exhibit a single migration peak in capillary electrophoresis, as well as to appropriate processes for the preparation of same.