Patent · US Expired

Monoclonal antibodies against type I phospholipase A.sub.2 as a diagnostic and anti-inflammatory therapeutic agent

US5767249A · kind A · utility

2Cited by

1References

5Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Werner Scheuer · Penzberg, DE
Christa Hubner-Parajsz · Tutzing, DE
Ulrich Tibes · Starnberg, DE

Key dates

Filing date	Aug 8, 1995
Grant date	Jun 16, 1998
Priority date	—
Expiry date	Aug 8, 2015

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/40
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention provides for monoclonal antibodies which specifically bind to type I phospholipase A.sub.2 for use as a diagnostic agent and as an anti-inflammatory therapeutic agent, which is particularly suitable for application in acute pancreatitis. The invention further provides for pharmaceutical compositions including the antibodies of the invention. The invention also provides for a method for treating subjects suffering from inflammatory symptoms and for detecting the activity of type I phospholipase A.sub.2 in a sample.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.