Process for producing 2-substituted optically active 2,3-dihydro-4H-pyran-4-one
US5767295A · kind A · utility
2Cited by
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17Claims
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Key dates
| Filing date | Jul 8, 1996 |
| Grant date | Jun 16, 1998 |
| Priority date | — |
| Expiry date | Jul 8, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/003
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides an efficient process for producing a 2-substituted optically active 2,3-dihydro-4H-pyran-4-one comprising subjecting an aldehyde, which is not bulky and cannot be expected an electronic interaction with a catalyst, such as acetaldehyde, and a Danishefsky diene to a highly enantio-selective asymmetric hetero Diels-Alder reaction in the presence of an asymmetric catalyst readily obtainable from inexpensive starting materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.