Patent · US Expired

Recombinant poxviruses with foreign DNA in essential regions

US5770212A · kind A · utility

50Cited by

9References

19Claims

0Family size

Assignee

Immuno Aktiengesellschaft · AT

Inventors

Falko-Günter Falkner · Orth an der Donau, AT
Georg Holzer · Paris, FR
Friedrich Dorner · Wien, AT

Key dates

Filing date	Feb 21, 1997
Grant date	Jun 23, 1998
Priority date	—
Expiry date	Feb 21, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2840/203
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Defective poxviruses that lack a function imparted by an essential region of its parental poxvirus are provided for protein production and vaccination. A DNA polynucleotide encoding a protein is inserted into the defective poxvirus and placed under transcriptional control of a promoter. The defective poxvirus is viable when the lost function of the essential region is complemented by a host cell, transgenic animal or helper virus.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.