Mutant E. coli strain with increased succinic acid production
US5770435A · kind A · utility
113Cited by
3References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 2, 1995 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Nov 2, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/849
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for isolating succinic acid producing bacteria is provided comprising increasing the biomass of an organism which lacks the ability to catabolize pyruvate, and then subjecting the biomass to glucose-rich medium in an anaerobic environment to enable pyruvate-catabolizing mutants to grow. The invention also provides for a mutant that produces high amounts of succinic acid, which as been derived from a parent which lacked the genes for pyruvate formate lyase and lactate dehydrogenase, and which belongs to the E.coli Group of Bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.