Peptides for reducing or inhibiting bone resorption
US5770565A · kind A · utility
14Cited by
9References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 8, 1994 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Sep 8, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides Arg-Gly-Asp peptides that can reduce or inhibit the binding of osteoclasts to a matrix such as bone or can selectively alter integrin receptor binding. The invention also provides methods of using the Arg-Gly-Asp peptides to reduce or inhibit osteoclast binding to a matrix, to reduce or inhibit bone resorption in a subject and to alter .alpha..sub.V .beta..sub.3 binding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.