Homogeneous water-in-perfluorochemical stable liquid dispersion for administration of a drug to the lung of an animal
US5770585A · kind A · utility
Inventors
Key dates
| Filing date | May 8, 1995 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | May 8, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0026
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to a homogenous water-in-perfluorochemical stable liquid dispersion for acceptable therapeutic administration of a drug to the lung of an animal. The dispersion includes a perfluorochemical liquid, water, surfactant and drug, wherein the water is homogeneously dispersed in the perfluorochemical to form a stable water-in-perfluorochemical liquid dispersion. The perfluorochemical constitutes greater than 50% by volume of the dispersion, and the drug is contained in the dispersion in an effective therapeutic amount. The invention further includes a method of delivering a drug to the lung of an animal. This aspect of the invention includes administering a stable homogenous water-in-perfluorochemical liquid dispersion to the animal lung or a section thereof. If desired, the method may further include delivering a breathable gas to the lung with a mechanical ventilator during the administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.