Method for treating leukemia with a hexa-cyclic compound
US5770605A · kind A · utility
4Cited by
4References
1Claims
0Family size
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Key dates
| Filing date | Mar 3, 1997 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Mar 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.