Hydrophobically-modified bioadhesive polyelectrolytes and methods relating thereto
US5770627A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Aug 16, 1995 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Aug 16, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Hydrophobically-modified bioadhesive polyelectrolytes containing a bioadhesive polyelectrolyte and a hydrophobic component are disclosed. Also disclosed are polyelectrolyte-agent compositions wherein the hydrophobically-modified bioadhesive polyelectrolyte is loaded with a pharmaceutically, cosmetically, or prophylactically acceptable agent. Suitable agents have hydrophobic and/or ionic character, and include drugs. The polyelectrolyte-agent compositions may be formulated for administration by topical, oral and/or systemic routes. Methods of administering such agents to an animal are also disclosed, and include administration of an effective amount of the polyelectrolyte-agent composition to the animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.