3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation

US5770758A · kind A · utility

Assignee

• Novartis AG · CH

Inventors

• Walter Kunz · Oberwil, CH
• Beat Jau · Aesch, CH

Key dates

• Filing date: Dec 20, 1996
• Grant date: Jun 23, 1998
• Expiry date: Dec 20, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D277/82
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula I ##STR1## and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III ##STR2## In the compounds of the formulae I and III: X is halogen, PA1 n is 0,1,2 or 3; PA1 Z is CN, CO-A or CS-A, PA1 A is hydrogen, halogen, OR.sub.1, SR.sub.2 and N(R.sub.3)R.sub.4 ; PA1 R.sub.1 to R .sub.4 are hydrogen, a substituted or unsubstituted, open-chain, saturated or unsaturated hydrocarbon radical containing not more than 8 carbon atoms, a substituted or unsubstituted cyclic, saturated or unsaturated hydrocarbon radical containing not more than 10 carbon atoms, substituted or unsubstituted benzyl or phenethyl, a substituted or unsubstituted alkanoyl group containing not more than 8 carbon atoms, a substituted or unsubstituted benzoyl group or a substituted or unsubstituted heterocyclyl radical; or R.sub.3 and R.sub.4, together with the nitrogen atom to which they are bonded, are a 5- or 6-membered, substituted or unsubstituted heterocyclic radical having 1-3 heteroatoms O,S and/or N. Processes for the preparation of compounds of the formula I are described…