Pharmaceutical compositions containing superoxide dismutase from Bacillus Stearothermophilus and Bacillus Caldotenax
US5772996A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 22, 1995 |
| Grant date | Jun 30, 1998 |
| Priority date | — |
| Expiry date | May 22, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition for use in the prophylaxis or treatment of pathological conditions resulting from the presence of superoxide radicals, comprising a manganese-superoxide dismutase (MnSOD) enzyme and a pharmaceutically acceptable excipient. The MnSOD enzyme is in native form and has substantially the amino acid sequence of SEQ ID NO: 17 or SEQ ID NO: 29 and is free of pyrogens consisting of macromolecular substances native to Bacillus Stearothermophilus (BS) or Bacillus Caldotenax (BC). Processes for producing the novel pharmaceutical composition and a method for the prophylaxis or treatment of pathological conditions resulting from the presence of superoxide radicals utilizing the novel composition are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.