Patent · US Expired

Combination therapy to treat osteoporosis - polyphosphonates and estrogen agonists

US5773477A · kind A · utility

5Cited by
7References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 21, 1997
Grant dateJun 30, 1998
Priority date
Expiry dateFeb 21, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61B2018/00148
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides novel methods of treating or preventing osteoporosis comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different provided that, when R.sup.1 and R.sup.2 are the same, each is a methyl or ethyl group, and, when R.sup.1 and R.sup.2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a bone resorption inhibiting polyphosphonate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.