N-N-(3,3-dimethylbutyl)-L-A-aspartyl!-L-hexahydrophenylalanine 1-methyl ester useful as a sweetening agent, its method of preparation
US5773640A · kind A · utility
4Cited by
1References
17Claims
0Family size
Inventors
Key dates
| Filing date | Nov 7, 1996 |
| Grant date | Jun 30, 1998 |
| Priority date | — |
| Expiry date | Nov 7, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06113
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel sweetening compound characterized in that it is N-N-(3,3-dimethylbutyl)-L-.alpha.-aspartyl!-L-hexahydrophenylalanine 1-methyl ester of formula: ##STR1## and its method of preparation characterized in that an aqueous/alcohol solution of pH 4.5-5 of aspartame and 3,3-dimethylbutyraldehyde at room temperature is treated with hydrogen at a pressure of 3 bars in the presence of a catalyst based on platinum such as platinum black and platinum oxide and in that the product formed is purified by precipitation and filtration after evaporation in vacuo of the alcohol part of the solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.