Methods and compositions for effecting homologous recombination
US5776744A · kind A · utility
24Cited by
0References
34Claims
0Family size
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jul 7, 1998 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/53
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods, compositions and kits for effecting homologous recombination are described. In one aspect, the method utilizes two introduced DNAs: (1) a mutagen-linked single-stranded oligonucleotide capable of specifically binding to double-stranded DNA to form a triple-stranded helix, and (2) a donor DNA fragment capable of undergoing homologous recombination with DNA targeted by the oligonucleotide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.