Oligonucleotides comprising a region of a cytokine suppressive anti-inflammatory drug binding protein

US5777097A · kind A · utility

Assignee

• SmithKline Beecham Limited · US

Inventors

• John Lee · San Antonio, US
• Jerry L. Adams · Wayne, US
• Timothy Francis Gallagher · Collegeville, US
• David W. Green · Via Enrico Fermi, US
• John Richard Heys · Malvern, US
• Peter Colon McDonnell · Cheltenham, US
• Dean E. McNulty · Philadelphia, US
• Peter Ronald Young · Conshohocken, US
• James E. Strickler · Milton, US

Key dates

• Filing date: Jun 6, 1995
• Grant date: Jul 7, 1998
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/136
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.