Gene-targeted mice with humanized A.beta. sequence and Swedish FAD mutation
US5777194A · kind A · utility
6Cited by
1References
5Claims
0Family size
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Key dates
| Filing date | Apr 23, 1996 |
| Grant date | Jul 7, 1998 |
| Priority date | — |
| Expiry date | Apr 23, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is non-human mouse homozygous for a targeted amyloid precursor protein-encoding gene comprising: (1) a human A.beta. peptide-encoding sequence in place of the native A.beta. peptide-encoding sequence; and (2) Swedish FAD mutations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.