Device for time lag focusing time-of-flight mass spectrometry
US5777325A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 6, 1996 |
| Grant date | Jul 7, 1998 |
| Priority date | — |
| Expiry date | May 6, 2016 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/025
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
A laser desorption ionization instrument for and method of measuring the molecular weight of large organic molecules includes a time of flight mass spectrometer (TOF MS). The TOF MS instrument provides optimized optic design for both DC and TLF modes. The invention further provides dynamic resolution enhancement for a given ejection pulse, along with optimized ion ejection pulses relative to the ion optic elements. The invention also provides means for compensating for difference in total kinetic energy among ions of different mass; high resolution detection means for improved sensitivity for large molecular weight species. The invention further provides x-y-z stage for sample presentation of both standard MALDI and gel or membrane based samples.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.