Methods for increasing the circulation half-life of protein-based therapeutics
US5780054A · kind A · utility
9Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 17, 1996 |
| Grant date | Jul 14, 1998 |
| Priority date | — |
| Expiry date | Jan 17, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of increasing the circulation half-life of protein-based therapeutics in a host, the methods comprising: (a) administering to the host an amount of a first liposome formulation comprising liposomes and an antineoplastic agent; and (b) administering to the host a second formulation comprising the protein-based therapeutic, wherein the amount of the first liposome formulation is sufficient to suppress an immune response to the protein-based therapeutic of the second formulation, thereby increasing the circulation half-life of the protein-based therapeutic.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.