Patent · US Expired

Sepsis, adult respiratory distress syndrome, and systemic inflammatory response syndrome diagnostic

US5780237A · kind A · utility

19Cited by
0References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 12, 1994
Grant dateJul 14, 1998
Priority date—
Expiry dateOct 12, 2014

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/92
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

There is disclosed a diagnostic assay for adult respiratory distress syndrome (ARDS), sepsis, multiple organ dysfunction (MOD) and systemic inflammatory response syndrome (SIRS), comprising (a) measuring the amount of selected unsaturated free fatty acids (FFAs) and saturated FFAs in a body fluid, and (b) determining a ratio value comprising the sum of the unsaturated FFAs divided by the sum of the saturated FFAs. There is further disclosed a diagnostic assay for ARDS, sepsis, MOD and SIRS, comprising (a) measuring the amount of 9- or 13-hydroxyoctadecadienoic acid (HODE) and 5-hydroxy-6-trans-8,11,14-cis-eicosatetraenoic acid (5-HETE) in a body fluid, and (b) determining a ratio value of HETE and HODE.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.