Immunoassays to detect antiphospholipid antibodies
US5780319A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 19, 1996 |
| Grant date | Jul 14, 1998 |
| Priority date | — |
| Expiry date | Apr 19, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Liposome reagents used in assays to detect the presence or amount of an analyte in a test sample, particularly where the analyte is antiphospholipid antibodies are described. The liposome reagents comprise a liposome, a ligand chosen to bind specifically with the analyte and associated with the liposome membrane, and a haptenated component associated with the membrane of the liposome where the hapten is chosen to bind specifically to a receptor bound to a solid phase or to a label compound that is an element of a signal detection system and where the liposome reagent is prepared so that during the assay the linkage between the solid phase and ligand of the liposome reagent is maintained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.