Methods for treating prostate cancer with LHRH-R antagonists
US5780435A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1995 |
| Grant date | Jul 14, 1998 |
| Priority date | — |
| Expiry date | Dec 15, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for treating prostate cancer are disclosed. The methods of the invention generally feature administration to a subject of an LHRH-R antagonist, in combination with a second therapy. In one embodiment, this second therapy is performance of a procedure that removes or destroys prostatic tumor tissue, such as a radical prostatectomy, cryosurgery or X-ray therapy (external or interstitial). In another embodiment, the second therapy is treatment with an LHRH-R agonist, either simultaneous with or subsequent to LHRH-R antagonist therapy. The methods of the invention can further involve administering an antiandrogen and/or an inhibitor of sex steroid biosynthesis to the subject in combination with the LHRH-R antagonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.