Patent · US Expired

Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors

US5780676A · kind A · utility

39Cited by
18References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateJul 14, 1998
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2602/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and poiyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.