Antibody-induced apoptosis
US5783186A · kind A · utility
182Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 5, 1995 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Dec 5, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to "tag" Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.