Homogeneous isolate of urabe mumps virus and vaccines containing the isolate
US5783194A · kind A · utility
3Cited by
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8Claims
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Key dates
| Filing date | Jan 30, 1996 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Jan 30, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/18734
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new attenuated substantially homogeneous Urabe mumps virus strain characterized by having a codon encoding glutamic acid at amino acid position 335 of the haemagglutinin-neuraminidase (HN) protein is provided. The codon may be GAA resulting in the abolition of an MseI restriction enzyme recognition site in the native virus. The invention also provides a gene encoding the HN (Glu-335) protein. The virus has utility in attenuated mumps vaccines, and as an antigen and immunogen in diagnostic embodiments.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.