Rapid screening method for effectors of signal transduction
US5783405A · kind A · utility
46Cited by
2References
12Claims
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Key dates
| Filing date | Oct 10, 1995 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Oct 10, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for assessing libraries of candidate modulators of intracellular signaling transmission pathways are described. The methods assess the ability of candidates from the library to inhibit the binding of peptides which represent participants in the signaling pathways as either a signal-generating protein or its cognate partner binding at a noncatalytic site. Specific peptides useful in this regard have been identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.