Piperidines and hexahydro-1H-azepines spiro substituted at the 4-position promote release of growth hormone
US5783582A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 16, 1997 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Jan 16, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Di and trisubstituted Piperidines, pyrrolidines and hexahydro-1H-azepines which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible mea products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such di- and trisubstituted piperidines and pyrrolidines as the active ingredient thereof are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.